BDBM20608 4-Hydroxytamoxifen::4-Hydroxytamoxifen (9)::4-[(1Z)-1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl]phenol::AFIMOXIFENE::CHEMBL489::[3H]4-OHT::cid_449459

SMILES CC\C(=C(/c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1

InChI Key InChIKey=TXUZVZSFRXZGTL-QPLCGJKRSA-N

Data  9 KI  36 IC50  5 EC50

PDB links: 14 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20608   

TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University

LigandBDBM20608(4-Hydroxytamoxifen | 4-Hydroxytamoxifen (9) | 4-[(...)Copy SMILESCopy InChI

Affinity DataIC50:  2.00E+4nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLKEGGMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI